32 | Issues in news Important for UPSC
1).Issue in news: Cellular Senescence
Important for #UPSC CSE Prelims, GS-3
Why in news: Study finds how body’s anti-viral immune response may eliminate aging cells.
About it:
It refers to a state of stable cell cycle arrest in which proliferating cells become resistant to growth-promoting stimuli, typically in response to DNA damage.
During this phase, the cell undergoes numerous phenotypic and metabolic changes.
Senescent cells accumulate during ageing and have been implicated in promoting a variety of age-related diseases.
Cellular senescence can compromise tissue repair and regeneration, thereby contributing towards ageing.
Removal of senescent cells can attenuate age-related tissue dysfunction and extend health span.
Senescence can also act as a potent anti-tumour mechanism by preventing the proliferation of potentially cancerous cells.
2) Issue in news: Corporate Debt Market Development Fund (CDMDF)
Important for #UPSC CSE Prelims, GS-3
Why in news: Sebi to set up corp debt mkt development fund with Rs 3,000 crore initial corpus from MFs.
About it:
The CDMDF is a backstop facility for specified debt funds during market dislocations.
The fund is intended to provide liquidity support in the event of a financial crisis.
Aim: to instil confidence amongst the participants in the corporate bond market and to generally enhance secondary market liquidity.
The proposed CDMDF will have an initial corpus of Rs 3,000 crore contributed by mutual funds.
The government has approved a 10-time leverage of the fund (Additional corpus), thus CDMDF may raise funds up to Rs 30,000 crore.
Contributions to the fund can be done by the specified debt-oriented mutual fund schemes and asset management companies of mutual funds.
This fund is guaranteed by the National Credit Guarantee Trust Company (NCGTC) and the backstop facility will be managed by SBI Mutual Fund.
Specified mutual fund schemes will have access to the fund for selling securities during market dislocation.
This access is proportional to the contribution made to the fund at a mutual fund level.

